Connor Scott

Connor Scott

Research Assistant / D.Phil Student

Nuffield Department of Clinical Neurosciences


Connor Scott is a neuroscientist with over 8 years of human tissue experience, specialising in bringing traditional histology into the modern era by developing workflows to bridge neuropathology with multiple ‘omic’ technologies using surgical and post-mortem CNS material.

Scroll down to see a brief overview of his academic profile or click on the headings above to get a more in-depth view.


  • Neurodegeneration
  • Laser Capture Microdissection
  • Digital Pathology
  • Machine Learning
  • Proteomics / Transcriptomics


  • D.Phil (Oxon) in Clinical Neurosciences, (current)

    University of Oxford

  • BSc (Hons) in Biomedical Sciences, 2012

    University of Greenwich



Neuropathology - Human Tissue

Proteomics / Transcriptomics

RNAscope / Immunostaining

Laser Microdissection

Molecular Biology

Data Analysis


Image Analysis

Employment Experience


Research Assistant

Nuffield Department of Clinical Neurosciences - University of Oxford

Jun 2015 – Present Oxford

Responsibilities include:

  • Senior Research Scientist.
    Current projects: (1) selective vulnerability in amyotrophic lateral sclerosis, (2) early detection of Alzheimer’s Disease, (3) novel biomarker discovery in Alzheimer’s disease, (4) microproteomics of rare neuronal cell types/tumour samples, (5) genetic classification of gliomas, (6) High-resolution MRI scanning.

  • Establishing, managing, and maintaining several core research facilities within NDCN. This includes providing training and troubleshooting.
    Facilities: Whole Slide Digital Imaging, Automated IHC/ISH and Laser Microdissection.

  • Day to day advisory role for post-graduates (MSc, MRes, D.Phil) and post-doctoral scientists.

  • Specialized training to students (undergraduates/postgraduates) and professionals (laboratory technicians, research assistants, post-doctoral researchers).

  • Supervisory role on several FHS research projects; both for medical students and undergraduates. Experience managing students, determining project direction, placing deadlines, managing student concerns, and helping students reach their targets.

    Click Employment Experience for a detailed summary.


Research Grant - £5000

For research to support the advancement of Neuropathology. In this case - Single-cell RNA-Sequencing of post-mortem motor neurons.

Public Engagement Award - £1000

Grant awarded to allow us to partake in an educational programme to perform hands-on science experiments with students, explain our research, and provide scientific career advice.

NIHR Oxford Biomedical Research Centre Training Bursary - £5000

This scheme funds short courses or modules which will provide training and expertise in research skills or research management.

Partnership Progression Scholarship

This Scholarship is awarded to the 10 highest achieving students that achieve a first-class honour in all academic years during their studies.



Sir Charles Sherrington and Sir Wilfrid Le Gros Clark Collections

Digital microscopist for these historic collections. Click for more information.

University of Oxford, Graduate President.

President of graduate students at one of University of Oxford’s colleges - Somerville College. Click for more information.

University of Oxford, Social Secretary.

Social Secretary - Somerville College. Click for more information.

Neuropath EQA scheme (NEQAS)

The Neuropathology EQA scheme (NEQAS) forms part of a national system of quality assurance to healthcare organisations that is being maintained and improved. Click for more information.

Editor - English Editing Service

With regard scientific papers, MogoEdit provides two editing models: standard polishing and in-depth editing. Standard paper polishing mainly focuses on correcting errors in language, including word use, expressions, grammar, and sentence structure.

Recent Publications

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Abstracts & Posters

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Spatially resolved MALDI mass spectrometric imaging of human brain tissue for metabolites, lipids, and peptides - proof of principle

In this proof of principle experiment, we demonstrate that MALDI-MSI combined with classical LCM LC-MS/MS has the potential to spatially resolve metabolic signatures in human brain at cellular resolution. Abstract & Talk given - The Oxford Metabolic Health Symposium 2020, 30th June – 3rd July 2020.

Molecular imaging of human brain tumour tissue by mass spectrometry

LC-MS based mass spectrometry imaging of proteins has the potential to provide novel insights into the proteome of tissues. Abstract - Presented at the Oxford Metabolic Health Symposium 2020, 30th June – 3rd July 2020.

High throughput, spatially-resolved proteomic analysis of a human brain tumour

Here we apply a sensitive, spatially resolved workflow for the proteomic analysis of a tumour to identify proteins that display spatial expression patterns within the tissue in an unsupervised manner. Abstract and Poster - ASMS Conference on Mass Spectrometry and Allied Topics, May 31st - June 4th 2020.

The BigMac dataset - linking tissue microstructure with diffusion MRI signals throughout the brain

Linking tissue microstructure with diffusion MRI signals throughout the brain Abstract and Poster - Whistler Scientific Workshop on Brain Functional Organization, Connectivity, and Behavior, March 1st - March 4th 2020.

Understanding the pathophysiological role of early tau aggregates in Alzheimer's disease by their direct visualisation in situ

Presented at 121st Meeting of the British Neuropathological Society, Developmental Neuropathology Symposium, 4th – 6th March 2020. Published Poster - Journal of Neuropathology and Applied Neurobiology.


  • Neuropathology Department, Level One, West Wing, John Radcliffe Hospital, Oxford, Oxfordshire OX3 9DU
  • Enter either West Wing or Children’s Hospital Entrance, go to Level One and ring the bell.
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